The Genomic Atlas of Breast Cancer — the non-coding theme
| Chr | chr14 |
| start | 100779410 |
| end | 100861031 |
| lncRNA name | MEG3 |
| entrez id | 55384 |
| hgnc id | HGNC:14575 |
| ensg id | ENSG00000214548 |
| refseq id | NR_002766 |
| methods | qPCR, Western blot etc. |
| regulated | down-regulated |
| function description | Here, we showed that MEG3 was downregulated in breast cancer tissues and cell lines. Collectively, these results suggest that MEG3 might suppress the tumor growth and angiogenesis via AKT signaling pathway and MEG3 may serve as a potential novel diagnostic and therapeutic target of breast cancer. |
| pubmed id | 28635399 |
| year | 2017 |
| title | Overexpression of long non-coding RNA MEG3 suppresses breast cancer cell proliferation, invasion, and angiogenesis through AKT pathway |
| drug | X |
| circulating | X |
| survival | X |
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