The Genomic Atlas of Breast Cancer — the non-coding theme

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  • GABC update 2020.06.15
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  • GABC online 2018.08.09
  • Data collection 2018.04.09

About Us

  • Steven Xi Chen:
    steven.chen@miami.edu
  • Yunpeng Zhang:
    YXZ1418@med.miami.edu
  • Peng Wang:
    wpgqy@163.com
  • Shangwei Ning:
    ningsw@ems.hrbmu.edu.cn
  • Xia Li:
    lixia@hrbmu.edu.cn

Detail


Chr chr12
start 97430884
end 97598415
lncRNA name NCRMS
entrez id 196475
hgnc id HGNC:29893
ensg id ENSG00000255794
refseq id NR_024037
methods qPCR, mmicroarray
regulated down-regulated
function description RMST played its biological function through regulating the mRNA or protein expression in cytoplasm.RMST could slow down the proliferation of TNBC cells to influence the tumor progression.RMST could enhance cell apoptosis in TNBC. The cell cycle detected by FCM assay indicated that RMST might induce the block of G0/G1 phase thus inhibiting TNBC cell proliferation.RMST overexpression could also restrain the invasion and migration abilities of TNBC cells.
pubmed id 29215701
year 2017
title Long non-coding RNA (LncRNA) RMST in triple-negative breast cancer (TNBC):Expression analysis and biological roles research.
drug X
circulating X
survival X

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