Detail

Chr	chr11
start	65422774
end	65445540
lncRNA name	NEAT1
entrez id	283131
hgnc id	HGNC:30815
ensg id	ENSG00000245532
refseq id	NR_028272
methods	qPCR, ISH etc.
regulated	up-regulated
function description	Induction of NEAT1 in hypoxia also leads to accelerated cellular proliferation, improved clonogenic survival and reduced apoptosis, all of which are hallmarks of increased tumorigenesis. Furthermore, in patients with breast cancer, high tumor NEAT1 expression correlates with poor survival, all of which are hallmarks of increased tumorigenesis.
pubmed id	25417700
year	2014
title	Tumor hypoxia induces nuclear paraspeckle formation through HIF-2a dependent transcriptional activation of NEAT1 leading to cancer cell survival.
drug	X
circulating	X
survival	V