Detail

Chr	chr11
start	65422774
end	65445540
lncRNA name	NEAT1
entrez id	283131
hgnc id	HGNC:30815
ensg id	ENSG00000245532
refseq id	NR_028272
methods	qPCR, RNAi, Western blot, Luciferase reporter assay, MTT assay etc.
regulated	up-regulated
function description	lncRNA-NEAT1 was specifically upregulated in BC cell lines and promoted BC cell growth through targeting miR-101. Knockdown of NEAT1 inhibited the proliferation and DNA synthesis of human BC cell in vitro. In addition, the regulation of EZH2 by miR-101 was required in NEAT1 induced BC cell growth. These findings indicated that NEAT1 might suppress the tumor growth via miR-101 dependent EZH2 regulation.
pubmed id	28034643
year	2017
title	The long non-coding RNA NEAT1 interacted with miR-101 modulates breast cancer growth by targeting EZH2.
drug	X
circulating	X
survival	X