The Genomic Atlas of Breast Cancer — the non-coding theme

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  • GABC update 2020.06.15
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  • GABC online 2018.08.09
  • Data collection 2018.04.09

About Us

  • Steven Xi Chen:
    steven.chen@miami.edu
  • Yunpeng Zhang:
    YXZ1418@med.miami.edu
  • Peng Wang:
    wpgqy@163.com
  • Shangwei Ning:
    ningsw@ems.hrbmu.edu.cn
  • Xia Li:
    lixia@hrbmu.edu.cn

Detail


Chr chr9
start 33673504
end 33677499
lncRNA name PTENP1
entrez id 11191
hgnc id HGNC:9589
ensg id ENSG00000237984
refseq id NA
methods qPCR
regulated down-regulated
function description The expression of PTENP1 was significantly downregulated in both BC tissues and cell lines.Overexpressed PTENP1 could significantly increase the abilities of cell survival,colony forming, migration and invasion but decrease apoptosis in BC cell lines.PTENP1 performed a negative role in the development of BC via downregulating miR-19 through PTEN-PI3K/Akt pathway.
pubmed id 29212574
year 2017
title Over-expression of long non-coding RNA PTENP1 inhibits cell proliferation and migration via suppression of miR-19b in breast cancer cells.
drug X
circulating X
survival V

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