The Genomic Atlas of Breast Cancer — the non-coding theme

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About Us

  • Steven Xi Chen:
    steven.chen@miami.edu
  • Yunpeng Zhang:
    YXZ1418@med.miami.edu
  • Peng Wang:
    wpgqy@163.com
  • Shangwei Ning:
    ningsw@ems.hrbmu.edu.cn
  • Xia Li:
    lixia@hrbmu.edu.cn

Detail


Chr chr3
start 180989762
end 181836880
lncRNA name SOX2OT
entrez id 347689
hgnc id HGNC:20209
ensg id ENSG00000242808
refseq id NR_004053
methods qPCR etc.
regulated up-regulated
function description We screened the expression level of two novel transcripts, SOX2OT-7 and SOX2OT-8 in five selected human cancer cell lines (HeLa, MCF7, HepG2, U-87 MG and NT2) by Real time RT-PCR. To facilitate the comparison of cell lines, HeLa cell line (which showed the least expression values) was considered as calibrator. Unexpectedly, all tested cancer cell lines, especially NT2 showed high levels of SOX2OT-7 and SOX2OT-8 expressions; except Mcf-7 which expresses the minimum level of SOX2OT-8.
pubmed id 26703382
year 2016
title Identification of new SOX2OT transcript variants highly expressed in human cancer cell lines and down regulated in stem cell differentiation.
drug X
circulating X
survival X

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