Chr | chr3 |
start | 116709235 |
end | 116723581 |
lncRNA name | TUSC7 |
entrez id | 285194 |
hgnc id | HGNC:27701 |
ensg id | ENSG00000243197 |
refseq id | NR_015391 |
methods | qPCR, RNAi, Western blot, ChIP, Luciferase reporter assay, Cell proliferation assay, ISH etc. |
regulated | differential expression |
function description | To evaluate the biological consequence of p53 induction of loc285194 and the role of loc285194 in tumorigenesis, we ectopically expressed loc285194 in HCT-116 WT and MCF-7 cells for cell proliferation assays. As expected, loc285194 significantly inhibited tumor cell growth. |
pubmed id | 23558749 |
year | 2013 |
title | LncRNA loc285194 is a p53-regulated tumor suppressor. |
drug | X |
circulating | X |
survival | X |
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