Detail

Chr	chr19
start	15828206
end	15836326
lncRNA name	UCA1
entrez id	652995
hgnc id	HGNC:37126
ensg id	ENSG00000214049
refseq id	NR_015379
methods	qPCR, Western blot, Northern blot, Flow cytometry assay etc.
regulated	up-regulated
function description	Results from Northern blot analysis indicated that CUDR was detectable only in human placenta but not in other normal tissues. For expression in human cancer cells, CUDR was detected in most cells of different tissue origins. CUDR mRNA was detected in human hepatocellular carcinoma HepG2 and Hep3B cells, human breast carcinoma MCF-7 and MDA-468 cells, human squamous carcinoma HeLa cells, human colon carcinoma HT-29 and CaCO-2 cells, as well as human lung carcinoma Calu-6 cells. However, CUDR was barely detectable in human prostate carcinoma PC3 cells. The differential expression of CUDR between human normal and cancer tissues is further demonstrated in tissues from cancer patients.
pubmed id	17416635
year	2007
title	Induction of drug resistance and transformation in human cancer cells by the noncoding RNA CUDR.
drug	V
circulating	X
survival	X