Chr | chr19 |
start | 15828206 |
end | 15836326 |
lncRNA name | UCA1 |
entrez id | 652995 |
hgnc id | HGNC:37126 |
ensg id | ENSG00000214049 |
refseq id | NR_015379 |
methods | microarray, qPCR, RNAi, Western blot, RIP, Luciferase reporter assay etc. |
regulated | up-regulated |
function description | We found that UCA1 was upregulated in breast tumors compared with the normal breast tissue. In contrast, p27 was downregulated in breast tumors, which was derived from the same core. This negative correlation between UCA1 and p27 was further supported by the data from breast cancer TMA. |
pubmed id | 24457952 |
year | 2014 |
title | Long non-coding RNA UCA1 promotes breast tumor growth by suppression of p27 (Kip1). |
drug | X |
circulating | X |
survival | X |
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