The Genomic Atlas of Breast Cancer — the non-coding theme

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  • GABC update 2020.06.15
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  • GABC online 2018.08.09
  • Data collection 2018.04.09

About Us

  • Steven Xi Chen:
    steven.chen@miami.edu
  • Yunpeng Zhang:
    YXZ1418@med.miami.edu
  • Peng Wang:
    wpgqy@163.com
  • Shangwei Ning:
    ningsw@ems.hrbmu.edu.cn
  • Xia Li:
    lixia@hrbmu.edu.cn

Detail


Chr chr19
start 15828206
end 15836326
lncRNA name UCA1
entrez id 652995
hgnc id HGNC:37126
ensg id ENSG00000214049
refseq id NR_015379
methods microarray, qPCR, RNAi, Western blot, RIP, Luciferase reporter assay etc.
regulated up-regulated
function description We found that UCA1 was upregulated in breast tumors compared with the normal breast tissue. In contrast, p27 was downregulated in breast tumors, which was derived from the same core. This negative correlation between UCA1 and p27 was further supported by the data from breast cancer TMA.
pubmed id 24457952
year 2014
title Long non-coding RNA UCA1 promotes breast tumor growth by suppression of p27 (Kip1).
drug X
circulating X
survival X

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