Chr | chrX |
start | 73820651 |
end | 73852753 |
lncRNA name | XIST |
entrez id | 7503 |
hgnc id | HGNC:12810 |
ensg id | ENSG00000229807 |
refseq id | NR_001564 |
methods | microarray, FISH etc. |
regulated | differential expression |
function description | The intratumoral and intertumoral variability in XIST RNA domain number in BRCA1 tumors correlates with chromosomal genetic abnormalities, including gains, losses, reduplications, and rearrangements of the X-chromosome. Finally, we also show the necessity for combined global and single-cell approaches in the assessment of tumors with such a high degree of heterogeneity. |
pubmed id | 17545591 |
year | 2007 |
title | X inactive-specific transcript RNA coating and genetic instability of the X chromosome in BRCA1 breast tumors. |
drug | X |
circulating | X |
survival | X |
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