Chr | chr3 |
start | 98497912 |
end | 98523066 |
lncRNA name | Z38 |
entrez id | 56650 |
hgnc id | HGNC:1322 |
ensg id | ENSG00000080822 |
refseq id | NA |
methods | qPCR, Western blot etc. |
regulated | up-regulated |
function description | In the current study, a newly found lncRNA Z38, which was identified through combining experiments of suppression subtractive hybridization (SSH) and reverse dot-blotting, was found to have high expression in breast cancer. More importantly, inhibiting Z38 expression by gene silencing greatly suppressed breast cancer cell proliferation and tumorigenesis, and treatment with Z38 siRNAs significantly induced cell apoptosis and inhibited tumor growth. |
pubmed id | 27053956 |
year | 2016 |
title | High Expression of the Newly Found Long Noncoding RNA Z38 Promotes Cell Proliferation and Oncogenic Activity in Breast Cancer |
drug | X |
circulating | X |
survival | X |
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