Chr | chr20 |
start | 49278178 |
end | 49295738 |
lncRNA name | ZFAS1 |
entrez id | 441951 |
hgnc id | HGNC:33101 |
ensg id | ENSG00000177410 |
refseq id | NR_003604 |
methods | microarray, Northern blot, ISH etc. |
regulated | down-regulated |
function description | The result shows ZFAS1 expression is decreased in ductal carcinoma relative to normal epithelial cells. We propose a functional role for Zfas1/ ZFAS1 in the regulation of alveolar development and epithelial cell differentiation in the mammary gland, which, together with its dysregulation in human breast cancer, suggests ZFAS1 as a putative tumor suppressor gene. |
pubmed id | 21460236 |
year | 2011 |
title | SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancer. |
drug | X |
circulating | X |
survival | X |
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