Chr | chr18 |
start | 57054558 |
end | 57072119 |
lncRNA name | linc-ROR |
entrez id | 100885779 |
hgnc id | HGNC:43773 |
ensg id | ENSG00000258609 |
refseq id | NR_048536 |
methods | qPCR, Western blot, Luciferase reporter assay etc. |
regulated | up-regulated |
function description | Compared with immortalized MCF10A breast epithelial cells, lncRNA-ROR was highly expressed in MCF7 (nonresistant) and MDA-MB-231 (drug-resistant) cell lines. The lncRNA-ROR level was strongly elevated in the MDA-MB-231 cell line as compared to the MCF7 cell line, indicating that lncRNA-ROR can be involved in the development of breast cancer. |
pubmed id | 28063065 |
year | 2017 |
title | Effects of long noncoding RNA-ROR on tamoxifen resistance of breast cancer cells by regulating microRNA-205. |
drug | V |
circulating | X |
survival | X |
CopyRight © University of Miami, USA; Harbin Medical University, China