Chr | chr18 |
start | 57054558 |
end | 57072119 |
lncRNA name | linc-ROR |
entrez id | 100885779 |
hgnc id | HGNC:43773 |
ensg id | ENSG00000258609 |
refseq id | NR_048536 |
methods | qPCR |
regulated | up-regulated |
function description | Among lncRNAs, large intergenic non-coding RNA regulator of reprogramming (lincRNA-ROR or linc-ROR) is a member of subvariety of lncRNAs, was first discovered in induced pluripotent stem cells (iPSCs), and plays a central role in promoting survival in iPSCs and embryonic stem cells (ESCs) through preventing the activation of cellular stress pathways.And linc-ROR also acts as a ceRNA to increase stemness gene Nanog expression by sponging miR-145 in cancer cells. |
pubmed id | 28869448 |
year | 2017 |
title | Large intergenic non-coding RNA-ROR as a potential biomarker for the diagnosis and dynamic monitoring of breast cancer |
drug | V |
circulating | V |
survival | V |
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