Chr | NA |
start | NA |
end | NA |
lncRNA name | lncRNA-HIT |
entrez id | NA |
hgnc id | NA |
ensg id | NA |
refseq id | NA |
methods | qPCR, Luciferase reporter assay etc. |
regulated | up-regulated |
function description | The level of expression of lncRNA-HIT in normal breast tissue was low and gradually increased to invasive carcinoma suggesting lncRNA-HIT may play a role in tumor progression in humans. These data further support the findings demonstrating the involvement of lncRNA-HIT in EMT and invasion as observed in NMuMG and 4T1 cells, and suggest that conserved human lncRNA-HIT could play a pivotal role in breast cancer metastasis. |
pubmed id | 25605728 |
year | 2015 |
title | Long non-coding RNAs regulated by TGFB1 lncRNA-HIT mediated TGFB1-induced epithelial to mesenchymal transition in mammary epithelia. |
drug | X |
circulating | X |
survival | X |
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