Detail

Chr	NA
start	NA
end	NA
lncRNA name	uc.38
entrez id	NA
hgnc id	NA
ensg id	NA
refseq id	NA
methods	qPCR, Western blot, RIP
regulated	down-regulated
function description	The expression of uc.38, a T-UCR, was down-regulated in both breast cancer tissues and breast cancer cell lines. uc.38 was expressed at significantly lower levels in larger tumours and tumours of more advanced stages.up-regulation of uc.38 expression inhibited cell proliferation and induced cell apoptosis.uc.38 suppressed breast cancer. uc.38 negatively regulated the expression of the pre-B-cell leukaemia homeobox 1 (PBX1) protein and subsequently affected the expression of Bcl-2 family members,ultimately inducing breast cancer cell apoptosis.The level of expression and type of TUCR have been shown to be closely related to the survival rates of patients with cancer.
pubmed id	29312798
year	2017
title	uc.38 induces breast cancer cell apoptosis via PBX1.
drug	X
circulating	X
survival	V