The Genomic Atlas of Breast Cancer — the non-coding theme
| Chr | chr1 |
| start | 41578954 |
| end | 41618413 |
| strand | - |
| Geng Symbol | SCMH1 |
| circRNA name | hsa_circ_0011946 |
| methods | qRT-PCR,Western Blot,etc. |
| regulated | up |
| Function Description | Taken together, these circRNA expression profile findings from high-throughput RNA sequencing technology showed 152 circRNAs changing remarkably in breast cancer tissues and the preliminarily determined hsa_circ_0011946 being a key regulator of breast cancer. The outcome of the biomath-ematical prediction and in vitro experiments manifested that the inactivation of the hsa_circ_0011946/RFC3 signaling pathway could inhibit the migration and invasion capacities of MCF-7 cells |
| PMID | 29593432 |
| year | 2018 |
| Title | Downregulation of hsa_circ_0011946 suppresses the migration and invasion of the breast cancer cell line MCF-7 by targeting RFC3. |
| drug | X |
| circulating | X |
| survival | X |
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