Detail

Chr	NA
start	NA
end	NA
strand	NA
Geng Symbol	NA
circRNA name	hsa_circ_0011946?
methods	RT-qPCR,Western blot,etc.
regulated	up
Function Description	In the present study, we utilized high-throughput sequencing and experimental validation in vitro to uncover the differentially expressed circRNAs in breast cancer tissues and cell lines and found that hsa_circ_0011946 was significantly upregulated. Moreover, a bioinformatics analysis showed RFC3 to be a target gene of hsa_circ_0011946. Furthermore, we downregulated hsa_circ_0011946 in the Michigan Cancer Foundation-7 (MCF-7) cell line and performed cell proliferation, migration, and invasion experiments, in order to elaborate on its function.
PMID	29593432
year	2018
Title	Downregulation of hsa_circ_0011946 suppresses the migration and invasion of the breast cancer cell line MCF-7 by targeting RFC3
drug	X
circulating	X
survival	X