The Genomic Atlas of Breast Cancer — the non-coding theme

Update News

  • GABC update 2020.06.15
  • GABC update 2019.03.20
  • GABC online 2018.08.09
  • Data collection 2018.04.09

About Us

  • Steven Xi Chen:
    steven.chen@miami.edu
  • Yunpeng Zhang:
    YXZ1418@med.miami.edu
  • Peng Wang:
    wpgqy@163.com
  • Shangwei Ning:
    ningsw@ems.hrbmu.edu.cn
  • Xia Li:
    lixia@hrbmu.edu.cn

Detail


Chr chr19
start 53158813
end 53164096
strand -
Geng Symbol ZNF83
circRNA name hsa_circ_0052112
methods qRT-PCR,luciferase assay,FISH,etc.
regulated up
Function Description In summary, our study revealed that hsa_circ_0052112 was up-regulated in MDA-MB-231 cells, and overexpression of hsa_-circ_0052112 contributed to the migration and invasion of breastcancer cells by functioning as a sponge for miR-125a-5p. Althoughexploring the potential clinicopathological significance of hsa_-circ_0052112 in breast cancer tissues remains insufficient, our resultssuggest hsa_circ_0052112 may serve as a novel biomarker and provide apotent therapeutic target of breast cancer.
PMID 30257349
year 2018
Title Circular RNA hsa_circ_0052112 promotes cell migration and invasion by acting as sponge for miR-125a-5p in breast cancer.
drug X
circulating X
survival V

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