The Genomic Atlas of Breast Cancer — the non-coding theme

Update News

  • GABC update 2020.06.15
  • GABC update 2019.03.20
  • GABC online 2018.08.09
  • Data collection 2018.04.09

About Us

  • Steven Xi Chen:
    steven.chen@miami.edu
  • Yunpeng Zhang:
    YXZ1418@med.miami.edu
  • Peng Wang:
    wpgqy@163.com
  • Shangwei Ning:
    ningsw@ems.hrbmu.edu.cn
  • Xia Li:
    lixia@hrbmu.edu.cn

Detail


Chr chr21
start 43782390
end 43786644
strand -
Geng Symbol TFF1
circRNA name hsa_circ_0061825
methods qRT-PCR,Western blot,FISH,RIP,Luciferase assay,etc.
regulated Down?
Function Description In summary, this investigation proved that circ©TFF1, which derived from the host gene TFF1, elicited an oncogenic function in breast cancer by freeing TFF1 from miR©326©induced silence (Figure 7G). The link between the modulatory mechanism of circ©TFF1©miR©326©TFF1 axis and cellular activities in breast cancer is revealed here for the first time, and our findings will offer a novel insight into the therapy of breast cancer patients.
PMID 31961997
year 2020
Title Circular RNA hsa_circ_0061825 (circ-TFF1) contributes to breast cancer progression through targeting miR-326/TFF1 signalling.
drug X
circulating X
survival V

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