The Genomic Atlas of Breast Cancer — the non-coding theme

Update News

  • GABC update 2020.06.15
  • GABC update 2019.03.20
  • GABC online 2018.08.09
  • Data collection 2018.04.09

About Us

  • Steven Xi Chen:
    steven.chen@miami.edu
  • Yunpeng Zhang:
    YXZ1418@med.miami.edu
  • Peng Wang:
    wpgqy@163.com
  • Shangwei Ning:
    ningsw@ems.hrbmu.edu.cn
  • Xia Li:
    lixia@hrbmu.edu.cn

Detail


Chr chr5
start 73069679
end 73076570
strand +
Geng Symbol RGNEF
circRNA name hsa_circ_0072995
methods qRT-PCR,Luciferase assay,etc.
regulated up
Function Description In summary, our study revealed that hsacirc0072995 was upregulated in MDA-MB-231 cells compared withMCF-7 cells, and overexpression of hsacirc0072995 promoted breast cancer cells migration and invasion by directsponge for miR-30c-2-3p. Nonetheless, conducting migration and invasion experiments in multiple breast cancercell lines, tissues or animals remains insufficient. Despite this, our results suggest that hsacirc0072995 may serveas a novel biomarker, and studying the molecular mechanisms by which circRNAs act as miRNA sponges mayrepresent a new direction to regulate the development of breast cancer
PMID 30182731
year 2018
Title Circular RNA hsa_circ_0072995 promotes breast cancer cell migration and invasion through sponge for miR-30c-2-3p.
drug X
circulating X
survival V

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