Chr | chr5 |
start | 73069679 |
end | 73076570 |
strand | + |
Geng Symbol | RGNEF |
circRNA name | hsa_circ_0072995 |
methods | qRT-PCR,Luciferase assay,etc. |
regulated | up |
Function Description | In summary, our study revealed that hsacirc0072995 was upregulated in MDA-MB-231 cells compared withMCF-7 cells, and overexpression of hsacirc0072995 promoted breast cancer cells migration and invasion by directsponge for miR-30c-2-3p. Nonetheless, conducting migration and invasion experiments in multiple breast cancercell lines, tissues or animals remains insufficient. Despite this, our results suggest that hsacirc0072995 may serveas a novel biomarker, and studying the molecular mechanisms by which circRNAs act as miRNA sponges mayrepresent a new direction to regulate the development of breast cancer |
PMID | 30182731 |
year | 2018 |
Title | Circular RNA hsa_circ_0072995 promotes breast cancer cell migration and invasion through sponge for miR-30c-2-3p. |
drug | X |
circulating | X |
survival | V |
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