The Genomic Atlas of Breast Cancer — the non-coding theme

Update News

  • GABC update 2020.06.15
  • GABC update 2019.03.20
  • GABC online 2018.08.09
  • Data collection 2018.04.09

About Us

  • Steven Xi Chen:
    steven.chen@miami.edu
  • Yunpeng Zhang:
    YXZ1418@med.miami.edu
  • Peng Wang:
    wpgqy@163.com
  • Shangwei Ning:
    ningsw@ems.hrbmu.edu.cn
  • Xia Li:
    lixia@hrbmu.edu.cn

Detail


Chr chr14
start 97312431
end 97327072
strand +
Geng Symbol VRK1
circRNA name hsa_circ_0141206
methods Western blot,etc.
regulated Down?
Function Description In conclusion, the current work was the first to indicate the circRNA signature of BCSCs. We determined the circRNA/miRNA network and analysed the potential functional roles of dysregulated circRNAs. Furthermore, we revealed that circVRK1 was capable to negatively regulate the stemness of BCSCs. Our findings strengthen the possibility that circVRK1 is able to serve as a potential target for BCSCs. Additionally, the current data also provide supports for further study on circRNAs in stemness maintenance of BCSCs.
PMID 29221160
year 2017
Title Circular RNA profile indicates circular RNA VRK1 is negatively related with breast cancer stem cells
drug X
circulating X
survival X

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