The Genomic Atlas of Breast Cancer — the non-coding theme
| Chr | NA |
| start | NA |
| end | NA |
| strand | NA |
| Geng Symbol | NA |
| circRNA name | circASS1 |
| methods | qRT-PCR,luciferase assay,Western Blot,etc. |
| regulated | down |
| Function Description | In summary, our study suggests that circASS1 expression is significantly down-regulated in highly aggressive BCcells and circASS1 suppresses invasion and migration of BC by the sponge activity on miR-4443 and upregulationof ASS1 expression, implying its tumor suppressive role in BC development. The regulation of circASS1in vitroindicates that it may be a potential targeted therapy in BC |
| PMID | 30657346 |
| year | 2019 |
| Title | Circular RNA circASS1 Is Downregulated in Breast Cancer Cells MDA-MB-231 and Suppressed Invasion and Migration |
| drug | X |
| circulating | X |
| survival | X |
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