Chr | NA |
start | NA |
end | NA |
strand | NA |
Geng Symbol | NA |
circRNA name | circASS1 |
methods | qRT-PCR,luciferase assay,Western Blot,etc. |
regulated | Down? |
Function Description | Results: CircASS1 in MDA-MB-231 is downregulated comparing to MCF-7, and overexpression of circASS1 could suppress invasion and migration. While silence, it could promote invasion and migration. MiR-4443 functioning as a tumor promoter gene could be captured by circASS1. ASS1 is upregulated in loss-of-function experiments, while downregulated in gain-of-function experiments.Conclusion: CircASS1 suppresses invasion and migration capacity of breast cancer cells and harbored miR-4443. |
PMID | 30657346 |
year | 2019 |
Title | Circular RNA circASS1 is downregulated in breast cancer cells MDA-MB-231 and suppressed invasion and migration. |
drug | X |
circulating | X |
survival | X |
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