The Genomic Atlas of Breast Cancer — the non-coding theme
| Chr | NA |
| start | NA |
| end | NA |
| strand | NA |
| Geng Symbol | NA |
| circRNA name | circDENND4C |
| methods | Western blots,etc. |
| regulated | up |
| Function Description | Results: In breast cancer cells, circDENND4C was increased under hypoxic conditions and decreased after knocking-down HIF1¦Á. In addition, knocking-down circDENND4C inhibited proliferation of breast cancer cells in a hypoxic environment. Finally, tumors with a large size had higher circDENND4C expression levels than those of small size.Conclusion: CircDENND4C is a HIF1¦Á-associated circRNA promoting the proliferation of breast cancer cells under hypoxia. |
| PMID | 28739726 |
| year | 2017 |
| Title | HIF1¦Á-associated circDENND4C Promotes Proliferation of Breast Cancer Cells in Hypoxic Environment. |
| drug | X |
| circulating | X |
| survival | X |
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