Chr | NA |
start | NA |
end | NA |
strand | NA |
Geng Symbol | NA |
circRNA name | circIRAK3 |
methods | etc. |
regulated | differential expression |
Function Description | ncRNAs are dysregulated in breast cancer and miRNAs, noted for their stability, and lncRNAs arebeing investigated as biomarkers of disease pathology, prognostic indicators, and potential therapeutictargets, as well as modalities to block cancer progression and metastasis. We know much moreabout miRNAs than lncRNAs in human breast tumors. Our understanding of the networks betweenmiRNAs, lncRNAs, their interacting partners, and targets is expanding. However, individual andcombinations of miRNAs and lncRNAs have cell-specific activities that are not fully understood,nor is their interaction with the immune system, microbiome, microenvironment, hormonal milieu,or metabolome elucidated. Further investigation is needed to bring studies on miRNAs and lncRNAsinto clinical practice for diagnosis, prognosis, and therapeutics in breast cancer patients |
PMID | 30545127 |
year | 2018 |
Title | Non-Coding RNAs in Breast Cancer: Intracellular and Intercellular Communication. |
drug | X |
circulating | X |
survival | X |
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