The Genomic Atlas of Breast Cancer — the non-coding theme
| Chr | NA |
| start | NA |
| end | NA |
| strand | NA |
| Geng Symbol | NA |
| circRNA name | has_circ_000911 |
| methods | luciferase assay,qRT-PCR,etc. |
| regulated | up |
| Function Description | In conclusion, in this study, and to the best of our knowledge, we report for the first time that circRNA?000911 plays an anti?oncogenic role in breast cancer. Moreover, circRNA-000911 exerts its function by serving as a miRNA sponge for miR-449a and thereby promoting the function of Notch1 and the NF-¦ĘB signaling pathway. Therefore, circRNA-000911 may serve as a promising predictive biomarker and therapeutic target for patients with breast cancer |
| PMID | 29431182 |
| year | 2018 |
| Title | Comprehensive circular RNA profiling reveals the regulatory role of the circRNA-000911/miR-449a pathway in breast carcinogenesis. |
| drug | X |
| circulating | X |
| survival | V |
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