Detail

Chr	NA
start	NA
end	NA
strand	NA
Geng Symbol	NA
circRNA name	circCER
methods	Western blot,etc
regulated	down
Function Description	The present study aimed to evaluate the expression profiles of circRNA-CER in breast cancer and investigate their potential role in the disease. The data demonstrated that the expression levels of circRNA-CER in breast cancer tissue were significantly higher compared with in adjacent non-tumor tissue, and that circRNA-CER may function as a competing endogenous RNA to regulate the expression of MMP13 by competing with miR-136 in breast cancer cells. To the best of our knowledge the present study demonstrated for the first time a positive circRNA?CER/MMP13 association, and crosstalk among miR-136, circRNA-CER and MMP13, which provides novel insight into the treatment of breast cancer.
PMID	30816475
year	2019
Title	circRNA?CER mediates malignant progression of breast cancer through targeting the miR?136/MMP13 axis.
drug	X
circulating	X
survival	V