The Genomic Atlas of Breast Cancer — the non-coding theme

Update News

  • GABC update 2020.06.15
  • GABC update 2019.03.20
  • GABC online 2018.08.09
  • Data collection 2018.04.09

About Us

  • Steven Xi Chen:
    steven.chen@miami.edu
  • Yunpeng Zhang:
    YXZ1418@med.miami.edu
  • Peng Wang:
    wpgqy@163.com
  • Shangwei Ning:
    ningsw@ems.hrbmu.edu.cn
  • Xia Li:
    lixia@hrbmu.edu.cn

Detail


Chr chr13
start 43528083
end 43544806
strand -
Geng Symbol EPSTI1
circRNA name hsa_circ_0000479
methods Microarray,qRT-PCR,Luciferase assay,Western blot,etc.
regulated up
Function Description In summary, we have proposed a comprehensivemethod to systematically screen breast cancer specificcircular RNAs through integrating an in silico pipelinewith in vitro and ex vivo techniques. We highlighted thathsa_circ_001783 as a novel prognostic marker for breastcancer and uncovered its new mechanism in regulat-ing cancer proliferation and metastasis via sponging miR-200c-3p. Thus, this circular RNA might be a potentialtherapeutic target for breast cancer treatment.
PMID 30083277
year 2019
Title circEPSTI1 as a prognostic marker and mediator of triple-negative breast cancer progression.
drug X
circulating V
survival V

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