Detail

Chr	NA
start	NA
end	NA
strand	NA
Geng Symbol	NA
circRNA name	hsa_circ_0001098
methods	qRT-PCR,western blot,luciferase assay,etc.
regulated	down
Function Description	This study demonstrated the function of TCDD/cricRNA_BARD1/miR-3942-3p/BARD1 axis in breast cancer development for the first time. However, the internal mechanisms that TCDD up-regulated circRNA_BARD1 remain to be studied. Furthermore, the downstream signaling of BARD1 could be further explored. In conclusion, circRNA-BARD1 was remarkably up-regulated in breast cancer with TCDD treatment and inhibited carcinogenesis via regulating miR-3942-3p and BARD1. TCDD/cricRNA_BARD1/miR-3942-3p/BARD1 axis could be a novel regulator in the therapy of breast cancer.
PMID	30521417
year	2018
Title	Circlular RNA BARD1 (Hsa_circ_0001098) overexpression in breast cancer cells with TCDD treatment could promote cell apoptosis via miR-3942/BARD1 axis.
drug	X
circulating	X
survival	X