Chr | chr1 |
start | 116671746 |
end | 116671817 |
ID | MI0003776 |
miRNA_name | hsa-miR-320b-1 |
methods | qRT-PCR,Western blot,etc. |
regulated | differential expression |
Function Description | Expression of the Pten-miR-320-Ets2-regulated secretome distinguished human normal breast stroma from tumour stroma and robustly correlated with recurrence in breast cancer patients. This work reveals miR-320 as a critical component of the Pten tumour-suppressor axis that acts in stromal fibroblasts to reprogramme the tumour microenvironment and curtail tumour progression. |
PMID | 22179046 |
year | 2011 |
Title | Reprogramming of the Tumour Microenvironment by Stromal PTEN-regulated miR-320 |
drug | X |
circulating | X |
survival | V |
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