The Genomic Atlas of Breast Cancer — the non-coding theme

Update News

  • GABC update 2020.06.15
  • GABC update 2019.03.20
  • GABC online 2018.08.09
  • Data collection 2018.04.09

About Us

  • Steven Xi Chen:
    steven.chen@miami.edu
  • Yunpeng Zhang:
    YXZ1418@med.miami.edu
  • Peng Wang:
    wpgqy@163.com
  • Shangwei Ning:
    ningsw@ems.hrbmu.edu.cn
  • Xia Li:
    lixia@hrbmu.edu.cn

Detail


Chr chr1
start 116671746
end 116671817
ID MI0003776
miRNA_name hsa-miR-320b-1
methods qRT-PCR,Western blot,etc.
regulated differential expression
Function Description Expression of the Pten-miR-320-Ets2-regulated secretome distinguished human normal breast stroma from tumour stroma and robustly correlated with recurrence in breast cancer patients. This work reveals miR-320 as a critical component of the Pten tumour-suppressor axis that acts in stromal fibroblasts to reprogramme the tumour microenvironment and curtail tumour progression.
PMID 22179046
year 2011
Title Reprogramming of the Tumour Microenvironment by Stromal PTEN-regulated miR-320
drug X
circulating X
survival V

CopyRight © University of Miami, USA; Harbin Medical University, China