The Genomic Atlas of Breast Cancer — the non-coding theme

Update News

  • GABC update 2020.06.15
  • GABC update 2019.03.20
  • GABC online 2018.08.09
  • Data collection 2018.04.09

About Us

  • Steven Xi Chen:
    steven.chen@miami.edu
  • Yunpeng Zhang:
    YXZ1418@med.miami.edu
  • Peng Wang:
    wpgqy@163.com
  • Shangwei Ning:
    ningsw@ems.hrbmu.edu.cn
  • Xia Li:
    lixia@hrbmu.edu.cn

Detail


Chr chr14
start 101039690
end 101039755
ID MI0000776
miRNA_name hsa-miR-376c
methods etc.
regulated differential expression
Function Description In conclusion, this is the first study to associate circulating miR-127-3p, miR-376a and miR-652 with breast cancer. In addition,we have independently confirmed that miR-127-3p, miR-148b,miR-376a, miR-376c, miR-409-3p, miR-652 and miR-801 levelsare elevated in the plasma of breast cancer patients. ThesemiRNAs can differentiate even women with benign tumors, stage Ior stage II breast cancer from healthy controls thereby reinforcingtheir utility as minimally invasive, early detection markers. Thesubstantial accuracy of breast tumor detection makes thiscirculating miRNA panel a potentially useful (pre)screening tool,especially in younger women for whom mammography seems tobe less sensitive. But, further studies are necessary before thesefindings can be translated into clinical use.
PMID 24194846
year 2013
Title Plasma MicroRNA Panel for Minimally Invasive Detectionof Breast Cancer
drug X
circulating V
survival V

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