Chr | NA |
start | NA |
end | NA |
ID | NA |
miRNA_name | hsa-miR-801 |
methods | etc. |
regulated | differential expression |
Function Description | In conclusion, this is the first study to associate circulating miR-127-3p, miR-376a and miR-652 with breast cancer. In addition,we have independently confirmed that miR-127-3p, miR-148b,miR-376a, miR-376c, miR-409-3p, miR-652 and miR-801 levelsare elevated in the plasma of breast cancer patients. ThesemiRNAs can differentiate even women with benign tumors, stage Ior stage II breast cancer from healthy controls thereby reinforcingtheir utility as minimally invasive, early detection markers. Thesubstantial accuracy of breast tumor detection makes thiscirculating miRNA panel a potentially useful (pre)screening tool,especially in younger women for whom mammography seems tobe less sensitive. But, further studies are necessary before thesefindings can be translated into clinical use. |
PMID | 24194846 |
year | 2013 |
Title | Plasma MicroRNA Panel for Minimally Invasive Detectionof Breast Cancer |
drug | X |
circulating | V |
survival | V |
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