Detail

Chr	chr8
start	134800520
end	134800607
ID	MI0000441
miRNA_name	hsa-miR-30b
methods	qRT-PCR,etc.
regulated	differential expression
Function Description	Results:MicroRNA array analysis showed significant changes in miRNA expression in both CR and FA conditions innormal liver. Expression of miR-29 and miR-30 family members was increased in both CR and FA. Western blot analysisof the normal liver tissue showed that CR and FA downregulated the IGF-1/Akt pathway and qRT-PCR showed that theexpression of miR-29b, miR-29c, miR-30a and miR-30b were increased with CR and FA. Liver tissue collected from micein the breast cancer model showed an increase in expression of miR-29b, miR-29c and miR-30b while tumor tissueshowed increased expression of miR-29c, miR-30a and miR-30b.
PMID	32211051
year	2020
Title	Dietary alterations modulate the microRNA 29/30 and IGF-1/AKT signaling axis in breast Cancer liver metastasis.
drug	X
circulating	X
survival	V