Detail

Chr	NA
start	NA
end	NA
ID	NA
miRNA_name	hsa-miR-663
methods	qRT-PCR,etc.
regulated	up
Function Description	The exhilarating and fast-growing field of miRNAs and their ver-satilityintargetedtherapyagainstcancer,mayonedaybepracticable.Abnormal expression of miRNAs has been observed in most of thecancertype'srightthroughcancerearlierandlatestages.Thus,miRNAsportray as a very strong target in cancer therapy. Phytological-com-pound mediated therapy displayed a unique ability to modify miRNAslevel implicated in controlling pathobiology of cancer via transcrip-tional, miRNA processing and epigenetic mechanisms. These naturalcompoundsevaluatedbothin-vivoandinclinicaltrialsmightbeusedtotargetdiversesignalingpathwaysthroughspecificmiRNAs.Inaddition,phytological-compounds found to increase the chemo-sensitivity oftraditionaldrugsthroughmodulatingmiRNAs.Thesecompoundsmightbe subjugated for scheming therapeutic approaches in combinationwith traditional remedies to improve cancer therapies and prevention.Thereisanextensivescopeforthedevelopmentofphytochemicalintocommercial drugs to efficaciously prevent and treat cancer
PMID	31982837
year	2020
Title	Modification of miRNA Expression through plant extracts and compounds against breast cancer: Mechanism and translational significance.
drug	X
circulating	X
survival	X