Detail

Chr	chr2
start	132256966
end	132257080
ID	MI0006336
miRNA_name	hsa-miR-663b
methods	microarray,qRT-PCR,etc.
regulated	down
Function Description	In conclusion, this study revealed multiple deregulated miRNAs in BRCA1/2-associated breast carcinomas, some shared with sporadic breast carcinomas, but several possibly specific to BRCA1/2 carcinogenesis. Specific deregulated miRNAs in BRCA1/2-associated carcinomas appear to target similar pathways. This suggests the existence of common targetable miRNA regulated pathways driving BRCA1/2-associated breast carcinogenesis. These findings warrant further studies on the role of these miRNAs in BRCA1/2-associated breast carcinogenesis.
PMID	26378051
year	2015
Title	miRNA expression patterns in normal breast tissue and invasive breast cancers of BRCA1 and BRCA2 germ-line mutation carriers
drug	X
circulating	X
survival	X