Chr | chr17 |
start | 7017615 |
end | 7017701 |
ID | MI0000489 |
miRNA_name | hsa-miR-195 |
methods | qRT-PCR,etc |
regulated | up |
Function Description | We found that miR-16 is upregulated in patients comparedto the control group by the absolute quantification method.Consequently, miR-16 is not a suitable normaliser for the rel-ative expression profiling of miRNAs in luminal A breastcancer patients. in addition to miR-16, another five miRNAs(miR-145, miR-155, miR-451a, miR-21 and miR-486) werefound to be upregulated and one miRNA (miR-195) wasfound to be downregulated when analysed using absolutequantification. The combination of miR-145, miR-195 andmiR-486 resulted in the best diagnostic value (AUC = 0.875,sensitivity = 76% and specificity = 81%) for luminal A breastcancer |
PMID | 30840191 |
year | 2019 |
Title | Relative and Absolute Expression Analysis of MicroRNAs Associated With Luminal A Breast Cancer- A Comparison |
drug | X |
circulating | V |
survival | X |
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