The Genomic Atlas of Breast Cancer — the non-coding theme

Update News

  • GABC update 2020.06.15
  • GABC update 2019.03.20
  • GABC online 2018.08.09
  • Data collection 2018.04.09

About Us

  • Steven Xi Chen:
    steven.chen@miami.edu
  • Yunpeng Zhang:
    YXZ1418@med.miami.edu
  • Peng Wang:
    wpgqy@163.com
  • Shangwei Ning:
    ningsw@ems.hrbmu.edu.cn
  • Xia Li:
    lixia@hrbmu.edu.cn

Detail


Chr chr17
start 7017615
end 7017701
ID MI0000489
miRNA_name hsa-miR-195
methods qRT-PCR,etc
regulated up
Function Description We found that miR-16 is upregulated in patients comparedto the control group by the absolute quantification method.Consequently, miR-16 is not a suitable normaliser for the rel-ative expression profiling of miRNAs in luminal A breastcancer patients. in addition to miR-16, another five miRNAs(miR-145, miR-155, miR-451a, miR-21 and miR-486) werefound to be upregulated and one miRNA (miR-195) wasfound to be downregulated when analysed using absolutequantification. The combination of miR-145, miR-195 andmiR-486 resulted in the best diagnostic value (AUC = 0.875,sensitivity = 76% and specificity = 81%) for luminal A breastcancer
PMID 30840191
year 2019
Title Relative and Absolute Expression Analysis of MicroRNAs Associated With Luminal A Breast Cancer- A Comparison
drug X
circulating V
survival X

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